Question $28$

What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

Helicases and single$-$strand binding proteins work at the $5^{\text{'}}$ end.

The The origins of replication occur only at the $5\text{'}$ end.

DNA ligase works only in the $3^{\text{'}}{5}^{\text{'}}$ direction.

ONA polymerase can join new nucleotides only to the $3\text{'}$ end of a pre$-$existing strand, and the strands are antiparallel.