Question $6$

A basic drug is used in the treatment of gastroesophageal reflux disease $(pKa=3\mathrm{.}07).$ Determine the percentage of drug ionization

when administered intravenously $(pH=7\mathrm{.}4).$

Question $7$

An acidic drug is used as an antibiotic $($pKa $=4\mathrm{.}66).$ Determine the percentage of drug ionization in the stomach $(pH=2\mathrm{.}00).$

Question $8$

An acidic drug is used as an antibiotic $($ pKa$=4\mathrm{.}26).$ Determine the percentage of drug ionization when administered intravenously

$(pH=7\mathrm{.}40).$