QUESTIONS Chapter 3 (please answer a to I)

A). What are the main spectroscopic techniques used for structure determination?

B). Which nuclei lend themselves to NMR?

C). Why is the methylene in ethanol (CH3CH2OH) observed as a quartet in the H- NMR spectrum?

D). Why is the quartet seen as a ratio of 1:3:3:1?

E). What do you understand about the term 500MHz H- NMR spectrum?

F). What other sized instruments are available? What are the benets of each one?

G). Why is TMS used as an internal standard for running NMR spectra?

H). In mass spectrometry, what do you understand about the terms positive ion mode and negative ion mode?

I). In X-ray crystallography the compound of interest is often derivatized with the addition of a group containing a heavy atom. Give an example and explain the reason.