single IV bolus injection concentration containing 500 mg of cefamandole nafate (Mandol, Lilly) is given to...

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single IV bolus injection concentration containing 500 mg of cefamandole nafate (Mandol, Lilly) is given to an adult female patient (63 years, 55kg) for a septicemic infection. The apparent VD is 0.1 L/Kg and the elimination half-life is 0.75 hours. Assuming the drug is eliminated by first-order kinetics and may be described by a one-compartment model: What is the amount (mg) of drug in the body 4 hours after the dose is given? single IV bolus injection concentration containing 500 mg of cefamandole nafate (Mandol, Lilly) is given to an adult female patient (63 years, 55kg) for a septicemic infection. The apparent VD is 0.1 L/Kg and the elimination half-life is 0.75 hours. Assuming the drug is eliminated by first-order kinetics and may be described by a one-compartment model: What is the amount (mg) of drug in the body 4 hours after the dose is given?