Question: The basic 2 x 2 tables for exposure and disease is: Exposed Not exposed total Case 693 307 Control 320 680 total N OR =

The basic 2 x 2 tables for exposure and disease is:

Exposed

Not exposed

total

Case

693

307

Control

320

680

total

N

OR =

(4) Serum porcelain. (25 points)

Joke. Please laugh politely. Since there is no real variable that performs the way this one does, we have made it up. Suspend disbelief, and answer the questions as if this were a real variable. We have divided the group into those with a high serum porcelain and those with a low serum porcelain. The following table gives the proportion of persons in the main table who have a high serum porcelain (table 6)

Proportion with high serum porcelain

Exposed

Not exposed

total

Case

0.71

0.51

Control

0.31

0.74

total

For example, this means that 31% of exposed controls had a high serum porcelainetc.

From these two tables, construct the tables for potential confounding, calculated the stratum-specific ORs, the ORmh and answer the questions.

High serum porcelain

Low serum porcelain

Exposed

Not exposed

total

Exposed

Not exposed

total

Case

Case

Control

Control

total

total

OR1 = OR0 =

ORmh =

1. Is confounding present? If so, is it NEGATIVE or POSTIVE?

2. Is effect modification present?

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