Question: The table below from Putcha et al . ( 1 9 8 9 ) shows the average people ) plasma concentration of scopolamine over time

The table below from Putcha et al.(1989) shows the average people) plasma
concentration of scopolamine over time after intravenously injecting 0.4mg. Scopolamine is a
drug used to treat motion sickness.
Using these concentration data points and the provided two-compartment pharmacokinetic
model equation, calculate the following:.
Vplasma- The volume of the central compartment
A - The intercept of the distribution phase
B - The intercept of the elimination phase
ktp- The rate constant governing transfer of drug from peripheral to central compartment
Cplasma(t)=DdrugVplasma(A-B)[(ktp-B)e-Bt-(ktp-A)e-At]
where Ddrug=4108.
 The table below from Putcha et al.(1989) shows the average people)

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