Question: Use the data below for agonist (A) with a competitive antagonist (B) to produce a Schild plot. Once the shield plot is found, find the
Use the data below for agonist (A) with a competitive antagonist (B) to produce a Schild plot. Once the shield plot is found, find the pA2 value, and the Kd for the data.
| [A] for 50% biol effect | [B] |
| 7.50E-09 | 0 |
| 8.00E-09 | 1.00E-08 |
| 8.40E-09 | 1.80E-08 |
| 1.00E-08 | 5.00E-08 |
Please be thorough in your explanation, and include a schild plot in the explanation. I have having a very hard time understanding this concept.
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