Using the data table below. We've chosen the drug in green. Can you please answer the following?

Q.1 Draw the structures of two possible Phase I metabolites and two possible Phase II metabolites of your chosen drug. Name the type of metabolic reaction and the enzyme that catalyses it. What is the purpose of these biotransformations?

Side info that may help answer question - This is a group presentation assignment. We've chosen the drug highlighted in green on the table below for the following reasons: We recommend MiRo 22-709A for clinical testing as it is best for oral administration and low toxicity. 51% inhibition for its target enzyme. It has high GI absorption, can permeate BBB, does not have P-gp substrate, does not have any Lipinski violations and has high ionisation percentages at 5 8 pH. The other compounds dont meet one or more of the previously mentioned criteria. AChE Acetylcholinesterase is the target enzyme.

Table 3: Calculated and predicted properties the original hit, MiRe 22-401T, and three significant optimised leads