Question: What can you infer from this Manhattan plot about the gene ABCG2? Assume this was data from a GWAS looking at drug-resistance in cancer patients.
What can you infer from this Manhattan plot about the gene ABCG2? Assume this was data from a GWAS looking at drug-resistance in cancer patients. 30 ABCG2 25 20 15 SLC2A9 ... . .. . .. -log,P-value MYL2-CUX2 10 5 9 10 11 12 13 14 15 16 17 18 19 202122 Chromosome There are alleles on every chromosome that are significantly associated with this trait. You should further study the gene SLC2A9 in relation to this trait. O If you have the gene ABCG2 then you are more likely to have the trait than another person without the gene ABCG2. You should further study the gene ABCG2 in relation to this trait. There are 3 genes that determine drug-resistance in cancer patients
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