Question: Why is primase required for replication? Primase allows the RNA synthesis which provides the 3 ' O H required for the initiation of DNA polymerization
Why is primase required for replication?
Primase allows the RNA synthesis which provides the required for the initiation of DNA polymerization with DNA polymerase.
Primase allows the DNA polymerase to find the correct origin of replication in the DNA sequence.
Primase lays down the first initial DNA nucleotide which allows for DNA polymerase to add additional dNTPs via polymerization.
Primase is only required for transcription, as DNA replication can only requires the enzyme DNA polymerase, topoisomerase, and helicase.
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