... Zain JO 7:57 PM Done Assignment 2_b01659b6abd2... 1. Two formulations were prepared for paracetamol. Each formulation contains 100 mg of the drug. Formulation A contains drug particles with a size of Sum. Formulation contains drug particles with a size of 50 m. Answer the following: a. Which formulation will have a higher dissolution rate according to the Noyes-Whitney equation? b. How can we increase the dissolution rate for the two formulations? c. Formulation A was allowed to dissolve in 100 ml of water. After 5 minutes, 20 mg were completely dissolved in the bulk solution Calculate the dissolution rate (dM/dt) and calculate C (concentration of the drug in the bulk solution), Formulation A Formulation B 2. We are studying the diffusion of tetracycline across a cellulose membrane. The diffusion coefficient (D) of tetracycline is 8.0 * 10 cm/sec. The thickness of the membrane, h, is 2.40 * 10 cm. At steady state, the concentration in the donor compartment is 1.72 109 g/cm' and in the receptor compartment is 5 x 10*gm/cm'. Answer the following: a. When will the diffusion stop? b. Calculate the concentration gradient at steady state. c. Calculate the steady state flux (1) Ca Cr