Question: A short DNA sequence, which may be recognized by primase, is repeated many times throughout the E. coli chromosome. Researchers have hypothesized that primase may
A short DNA sequence, which may be recognized by primase, is repeated many times throughout the E. coli chromosome. Researchers have hypothesized that primase may recognize this sequence as a site to begin the synthesis of an RNA primer for DNA replication. The E. coli chromosome is roughly 4.6 million bp in length. How many copies of the primase recognition sequence would be necessary to replicate the entire E. coli chromosome?
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