Question: The biosynthesis of cholesterol as outlined in Figure 26.10 is admittedly quite complicated. It will aid your understanding of the process if you consider the
(a) Which carbon atoms of squalene 2, 3-epoxide correspond to the doubly bonded carbons of cholesterol?
(b) Which two hydrogen atoms of squalene 2, 3-epoxide are the ones that migrate in step 3?
(c) Which methyl group of squalene 2, 3-epoxide becomes the methyl group at the C, D ring junction of cholesterol?
(d) What three methyl groups of squalene 2, 3-epoxide are lost during the conversion of lanosterol to cholesterol?
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b The hydrogens that migrate in step 3 are those at C13 an... View full answer
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