The level of monoamine oxidase (MAO) activity in blood platelets (nm/mg protein/h) was determined for each individual

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The level of monoamine oxidase (MAO) activity in blood platelets (nm/mg protein/h) was determined for each individual in a sample of 43 chronic schizophrenics, resulting in x̅ = 2.69 and s1 = 2.30, as well as for 45 normal subjects, resulting in y̅ = 6.35 and s2 = 4.03. Does this data strongly suggest that true average MAO activity for normal subjects is more than twice the activity level for schizophrenics? Derive a test procedure and carry out the test using a 5 .01. [H0 and Ha here have a different form from the three standard cases. Let μ1 and μ2 refer to true average MAO activity for schizophrenics and normal subjects, respectively, and consider the parameter θ = 2 μ1 – μ2. Write H0 and Ha in terms of u, estimate u, and derive σ̂θ̂ (“Reduced Monoamine Oxidase Activity in Blood Platelets from Schizophrenic Patients,” Nature, July 28, 1972: 225–226).]

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