The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle
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The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle to yield CO2. When the body is stressed by prolonged starvation, however, acetyl CoA is converted into compounds called ketone bodies, which can he used by the brain as a temporary fuel. Fill in the missing information indicated by the four question marks in the following biochemical pathway for the synthesis of ketone bodies from acetylCoA:
Transcribed Image Text:
HSCOA H20 2 CH3ČSCOA CHзCCH,CsCoA CHзCCH,Cо- Acetyl CoA Acetoacetyl CoA Acetoacetate он CHаСсHз CHзснсH2со- Acetone 3-Hydroxybutyrate Ketone bodies
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