Question: What are the products of each of the following reactions? Your answer should account for all the amino acid residues in the starting peptides. (a)

What are the products of each of the following reactions? Your answer should account for all the amino acid residues in the starting peptides.
(a) Reaction of Leu-Gly-Ser with 1-fluoro-2, 4-dinitrobenzene
(b) Hydrolysis of the compound in part (a) in concentrated hydrochloric acid (100°C)
(c) Treatment of Ile-Glu-Phe with C6H5N=C=S, followed by hydrogen bromide in nitromethane
(d) Reaction of Asn-Ser-Ala with benzyloxycarbonyl chloride
(e) Reaction of the product of part (d) with p-nitrophenol and N,
N-dicyclohexylcarbodiimide
(f) Reaction of the product of part (e) with the ethyl ester of valine
(g) Hydrogenolysis of the product of part (f) over palladium

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a 1Fluoro24dinitrobenzene reacts with the amino group of the Nterminal amino acid in a nucleophilic aromatic substitution reaction of the additionelim... View full answer

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