You have isolated a temperature-sensitive mutant E. coli. At 34C, the growth rate is nearly normal but

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You have isolated a temperature-sensitive mutant E. coli. At 34°C, the growth rate is nearly normal but is reduced 10-fold at 37°C. You eventually discover that EF-Tu·GDP binding to the ribosome is two-fold higher in the mutant at 37°C. What aspect of translation is affected by the mutation?
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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