A clever new method of peptide synthesis involves formation of an amide bond by reaction of an
Question:
A clever new method of peptide synthesis involves formation of an amide bond by reaction of an -keto acid with an N-alkyl hydroxylamine:
The reaction is thought to occur by nucleophilic addition of the N-alkyl hydroxylamine to the keto acid as if forming an oxime (Section 19.8), followed by decarboxylation and elimination of water. Show themechanism.
Transcribed Image Text:
OH DMF co2 R' H20 R' co2 An a-keto acid A hydroxylamine An amide
Fantastic news! We've Found the answer you've been seeking!
Step by Step Answer:
Answer rating: 76% (13 reviews)
0 CO OH ...View the full answer
Answered By
Ashington Waweru
I am a lecturer, research writer and also a qualified financial analyst and accountant. I am qualified and articulate in many disciplines including English, Accounting, Finance, Quantitative spreadsheet analysis, Economics, and Statistics. I am an expert with sixteen years of experience in online industry-related work. I have a master's in business administration and a bachelor’s degree in education, accounting, and economics options.
I am a writer and proofreading expert with sixteen years of experience in online writing, proofreading, and text editing. I have vast knowledge and experience in writing techniques and styles such as APA, ASA, MLA, Chicago, Turabian, IEEE, and many others.
I am also an online blogger and research writer with sixteen years of writing and proofreading articles and reports. I have written many scripts and articles for blogs, and I also specialize in search engine
I have sixteen years of experience in Excel data entry, Excel data analysis, R-studio quantitative analysis, SPSS quantitative analysis, research writing, and proofreading articles and reports. I will deliver the highest quality online and offline Excel, R, SPSS, and other spreadsheet solutions within your operational deadlines. I have also compiled many original Excel quantitative and text spreadsheets which solve client’s problems in my research writing career.
I have extensive enterprise resource planning accounting, financial modeling, financial reporting, and company analysis: customer relationship management, enterprise resource planning, financial accounting projects, and corporate finance.
I am articulate in psychology, engineering, nursing, counseling, project management, accounting, finance, quantitative spreadsheet analysis, statistical and economic analysis, among many other industry fields and academic disciplines. I work to solve problems and provide accurate and credible solutions and research reports in all industries in the global economy.
I have taught and conducted masters and Ph.D. thesis research for specialists in Quantitative finance, Financial Accounting, Actuarial science, Macroeconomics, Microeconomics, Risk Management, Managerial Economics, Engineering Economics, Financial economics, Taxation and many other disciplines including water engineering, psychology, e-commerce, mechanical engineering, leadership and many others.
I have developed many courses on online websites like Teachable and Thinkific. I also developed an accounting reporting automation software project for Utafiti sacco located at ILRI Uthiru Kenya when I was working there in year 2001.
I am a mature, self-motivated worker who delivers high-quality, on-time reports which solve client’s problems accurately.
I have written many academic and professional industry research papers and tutored many clients from college to university undergraduate, master's and Ph.D. students, and corporate professionals. I anticipate your hiring me.
I know I will deliver the highest quality work you will find anywhere to award me your project work. Please note that I am looking for a long-term work relationship with you. I look forward to you delivering the best service to you.
3.00+
2+ Reviews
10+ Question Solved
Related Book For
Question Posted:
Students also viewed these Organic Chemistry questions
-
A process called helium burning is thought to occur inside older stars, forming carbon: 34He ( 12C If the reaction proceeds with 0.00781 g of mass lost on a molar basis, how much energy is given off?
-
The age of the universe is thought to be about 14 billion years. Assuming two significant figures, write this in powers of ten in (a) Years, (b) Seconds
-
Show how you might use a nucleophilic substitution reaction of 1-bromopropane to synthesize each of the following compounds. (You may use any other compounds that are necessary.) (a) (b)...
-
Does the EOQ increase or decrease if estimates of setup (order) costs include fixed, semi-variable, and pure variable costs while inventory-holding costs includes only pure variable costs? Vice...
-
The "You" Attitude Rewrite the following sentences to reflect your audience's viewpoint. 1. We request that you use the order form supplied in the back of our catalog. 2. We insist that you always...
-
A helium balloon hovers in midair, neither ascending nor descending. Is it in equilibrium? What forces act on it?
-
Consider the simple linear regression model fit to the rental price data from Problem 2.36. Data From Problem 2.36 Table B.24 contains data on median family home rental price and other data for 51 US...
-
Corporation XYZ has the following data on labor input and production of commodity Z for each of the eight production periods. 1. Use the data on labor input and total output to calculate the marginal...
-
1. Assume that OSG currently has accounts receivable of US $1 million from a US company which will be paid in three months. Explain and calculate how one might hedge the company's FX risk. Use the...
-
A. Richard McCarthy (born 2/14/64; Social Security number 100-10-9090) and Christine McCarthy (born 6/1/1966; Social security number 101-21-3434) have a 19-year-old son (born 10/2/99 Social Security...
-
Proteins can be cleaved specifically at the amide bond on the carboxyl side of methionine residues by reaction with cyanogen bromide, BrC = N. The reaction occurs in several steps: (a) The first step...
-
Arginine, the most basic of the 20 common amino acids, contains a guanidino functional group in its side chain. Explain, using resonance structures to show how the protonated guanidino group...
-
Find the volume of the largest box of the type shown in Figure 24, with one corner at the origin and the opposite corner at a point P = (x, y, z) on the paraboloid z = 1- X x 4 9 N with x, y, z 0 P y
-
Brad and Rochelle agree to form Sail Away, Inc., a small family boat rental business. Brad agrees to contribute 20 sailboats that he bought over many years (and had a lot of fun with!) with a total...
-
When a given elastic band is stretched 0.37 m it has 1.32 J of elastic potential energy stored in it. What is the force constant for the elastic band?
-
How much energy is consumed with running a 60W light for 6 hour and 15min?
-
Marketing Strategy portion of the plan (55) o A discussion on the new environmental running shoes you would introduce to Adidas portfolio as their marketing manager. (5) o The growth strategy that...
-
1. What are some of the differences between the metric system and the standard system? 2. Why is the metric system the preferred method of measurement in the world today? 3. In detail, explain why or...
-
The owner of the small business Wivenhoe Wines has completed a report analysing the results of the business for the quarter ended 31st December. He has compared the actual results with the original...
-
Why did management adopt the new plan even though it provides a smaller expected number of exposures than the original plan recommended by the original linear programming model?
-
A 0.135 M solution of a weak base has a pH of 11.23. Determine K b for the base.
-
Choline (Sec. 11.11) can be prepared by the reaction of trimethylamine with ethylene oxide. Write an equation for the reaction, and show its mechanism.
-
Acetylcholine is synthesized in the body's neurons. The enzyme choline acetyltransferase catalyzes its synthesis from acetyl-CoA (see "A Word About . . . Thioesters, Nature's Acyl-Activating Groups"...
-
Primary aliphatic amines (RNH2) react with nitrous acid in the same way that primary arylamines (ArNH2) do, to form diazonium ions. But alkyldiazonium ions RN2+ are much less stable than...
-
How truly do drive elements and social impact instruments, for example, social personality hypothesis and gathering polarization, deeply mold hierarchical way of behaving and decision-production at...
-
Sub Station and Planet Sub reported the following selected financial data ( $ in thousands ) . Sub Station s business strategy is to sell the best tasting sandwich with the highest quality...
-
The credit manager of Montour Fuel has gathered the following information about the company's accounts receivable and credit losses during the current year: Net credit sales for the year $ 7 , 5 0 0...
Study smarter with the SolutionInn App