Aldosterone is a hormone involved in maintaining fluid balance in the body. In a veterinary study, six dogs with heart failure were treated with the drug Captopril, and plasma concentrations of aldosterone were measured before and after the treatment. The results are given in the table below.34 Consider a sign test, using a non directional alternative, to investigate the claim that Captopril affects aldosterone level.

(a) What is the value of the test statistic?
(b) The p-value for the sign test is 0.031. If α = 0.10, what is your conclusion?

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Before 749 469 343 314 286 223 397.3 190.5 After 374 300 146 134 69 20 173.8 136.4 Difference 375 169 197 180 217 203 223.5 imal ean SD 2 76.1