DNA ligase has the ability to relax super-coiled circular DNA in the presence of AMP but not
Question:
(a) What is the mechanism of this reaction, and why does it depend on AMP?
(b) How could you determine that super-coiled DNA had in fact been relaxed?
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Related Book For
Biochemistry Concepts and Connections
ISBN: 978-0321839923
1st edition
Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews
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