Question: It is observed that as temperature is increased, most protein molecules go from their dened, folded state into a random-coil, denatured state that exposes more

It is observed that as temperature is increased, most protein molecules go from their defined, folded state into a random-coil, denatured state that exposes more hydrophobic surface area than is exposed in the folded state.
a. Given what you have learned so far about ∆H and ∆S, explain why this is reasonable.
b. Sometimes, however, proteins denature as temperature is decreased. How might this be explained?

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a We expect S for denaturation to be positive due to the increase ... View full answer

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