Question: Show how solid-phase peptide synthesis would be used to make Ile-Gly-Asn.

Show how solid-phase peptide synthesis would be used to make Ile-Gly-Asn.

Step by Step Solution

★★★★★

3.38 Rating (164 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock

i Me3COCNHCHCOO T CHCONH Bocasparagine Bocglycine CHC1 P Me3COCNHCHC0 ... View full answer

blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Document Format (1 attachment)

Word file Icon

893-C-O-O-C (2070).docx

120 KBs Word File

Students Have Also Explored These Related Organic Chemistry Questions!

Q:

The polymeric resin used for Merrifield solid-phase peptide synthesis (Section 26.8) is prepared by treating polystyrene with N-(hydroxymethyl) phthalimide and trifluoromethanesulfonic acid, followed...

Q:

Sometimes it is necessary in solid-phase peptide synthesis to use a resin linker that is more sensitive (that is, more reactive) to acid than the linker shown in Eq. 26.21 on p. 1285. The following...

Q:

The attachment of the N-protected C-terminal amino acid to the polymer in solid-phase peptide synthesis (Figure 17.7) is an SN2 displacement reaction. What is the nucleophile? What is the leaving...

Q:

Show how the solution-phase synthesis would be used to synthesize Ile-Gly-Asn.

Q:

help with this assingment: A decapeptide was examined by the following experiments. Edman's reagent releases Met. Carboxypeptidase A releases Leu. Tryptic digestion provides three peptides: Gly ,...

Q:

The first step in peptide synthesis is blocking (protection) of the amine functional group of an amino acid (a compound that contains both amine and carboxylic acid functional groups). Such a...

Q:

The detachment of the peptide chain from the polymer in solid-phase peptide synthesis (Figure 17.7) occurs by an acid-catalyzed SN2 mechanism. Write an equation to show this mechanism.

Q:

Show how the approach of solid phase peptide synthesis would be used to produce the Lysine-alanine dipeptide shown below. Your synthesis may utilize any monomeric amino acid starting materials...

Q:

Q5- Consider the following disaccharide: CH2OH 0 OH H H OH H O H H OH CH2 0 H H H OH H OH OH H OH a. Name the two monosaccharides that are formed on hydrolysis of the disaccharide? b. Describe the...

Q:

Q8- Show how you would use bromination followed by amination to synthesize the following amino acids. (a) glycine (b) leucine Q9- Show how the Gabriel-malonic ester synthesis could be used to make...

Q:

Pick two public companies; go to their Web sites, and identify their major strategies. Pick one of these companies and go to the Web site of a competitor in the same industry. For example, if you...

Q:

Teddy Bear Company sold a total of 30,000 stuffed tigers and lions. During August the following information was gathered: Tigers Lions $7.50S10.50 $5.50S10.50 69% 31% 75% 25% Actual selling price...

Q:

According to the Census Bureau, in October 2 0 1 6 , the average house price in the United States was $ 2 8 , 4 5 8 . 7 years earlier, the average price was $ 2 2 , 3 0 8 . What was theannual...

Q:

You have been assigned to a project in which the objectives are to expand three miles of the north-to-south highway through your city by two lanes in each direction. You are in charge of the...

Q:

In each of the following processes, give the products and classify each of the groups indicated by a colored label with one or more of the following terms: Bronsted base, Lewis base, Bronsted acid,...

Q:

The examples of incorrect curved-arrow notation in Fig. P3.36 were found in the notebooks of Barney Bottle brusher, a student who was known to have difficulty with organic chemistry. Explain what is...

Q:

Use the curved - arrow notation to derive three other resonance structures for anthracene. CC1..thmatummail three additional structures anthracene

Q:

Problem 9-20 Activity and Spending Variances (LO9-1, LO9-2, LO9-3] You have just been hired by FAB Corporation, the manufacturer of a revolutionary new garage door opening device. The president has...

Q:

Time valueYou have $1,500 to invest today at 7% interest compounded annually. a.Find how much you will have accumulated in the account at the end of (1) 3 years, (2) 6 years, and (3) 9 years. b.Use...

Q:

Refer to the bonds appearing in Figure 6.1. a. What is the coupon rate and year of maturity for the Qualcomm and Time Warner bonds? b. How much would you have had to pay to buy one Bank of America...