Question: Cell counts {Y i } are independent Poisson random variables, with i = E(Y i ). Consider the Poisson loglinear model log =

Cell counts {Yi} are independent Poisson random variables, with µi = E(Yi). Consider the Poisson loglinear model

log µ = Xθa, where µ = (µ1,..., µN).

Using arguments similar to those in Section 14.2, show that the large-sample covariance matrix of θ̂a can be estimated by [X’a diag(µ̂)Xa]–1, where µ̂ is the ML estimator of µ.

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