When explaining to a client the reasoning behind using combination therapy in the treatment of HIV, the nurse would include which of the following points?

a. The virus can remain dormant within the T cell for a very long time; it can mutate while in the T cell.

b. Adverse effects of many of the drugs used to treat this virus include immunosuppression, so the disease could become worse. 

c. The drugs are cheaper if used in combination. 

d. The virus slowly mutates with each generation. 

e. Attacking the virus at many points in its life cycle has been shown to be most effective. 

f. Research has shown that using only one type of drug that targeted only one point in the virus life cycle led to more mutations and more difficulty in controlling the disease.