During dietary restriction, amino acids may be used as metabolic fuels. In this process, glutamate is converted
Question:
During dietary restriction, amino acids may be used as metabolic fuels. In this process, glutamate is converted by glutamate dehydrogenase to α-ketoglutarate. α-Ketoglutarate binds to the β subunit of ATP synthase and inhibits its catalytic activity. Predict the effect of increased α-ketoglutarate on oxygen consumption and the production of reactive oxygen species.
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Increased levels of ketoglutarate can have several effects on cellular metabolism oxygen consumption ...View the full answer
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Related Book For 
Fundamentals Of Biochemistry Life At The Molecular Level
ISBN: 9781118918401
5th Edition
Authors: Donald Voet, Judith G Voet, Charlotte W Pratt
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