Combining both groups, compute the standardized RR for raloxifene vs. placebo and new fractures? Endocrinology A study

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Combining both groups, compute the standardized RR for raloxifene vs. placebo and new fractures?


Endocrinology

A study of raloxifene and incidence of fractures was conducted among women with evidence of osteoporosis. The women were initially divided into two groups: those with and those without pre-existing fractures. The women were then randomized to raloxifene or placebo and followed for 3 years to determine the incidence of new vertebral fractures, with the results shown in Table 13.53.

Table 13.53 Comparison of fracture incidence between raloxifene- and placebo-treated women

 No pre-existing fractures Pre-existing fractures No new fractures No new fractures Total New fractures New fractures Tot

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