Question: Use the FDR method to correct for multiple comparisons using an FDR = .05. Which SNPs show statistically significant effects? How do the results compare
Use the FDR method to correct for multiple comparisons using an FDR = .05. Which SNPs show statistically significant effects? How do the results compare with those in Problem 12.72?
Genetics, Diabetes
Suppose we have separately analyzed the effects of 10 SNPs comparing people with type I diabetes vs. controls. The p-values from these separate analyses are given in Table 12.44.
Table 12.44: Effects of 10 SNPs on type I diabetes

p-value p-value SNP SNP .04 .10 .40 .55 .34 .62 .001 .01 4 .80 .005 10
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We first reorder the SNPs by size of the nominal pvalue as shown below We no... View full answer
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