Question: Use the FDR method to correct for multiple comparisons using an FDR = .05. Which SNPs show statistically significant effects? How do the results compare

Use the FDR method to correct for multiple comparisons using an FDR = .05. Which SNPs show statistically significant effects? How do the results compare with those in Problem 12.72? 


Genetics, Diabetes

Suppose we have separately analyzed the effects of 10 SNPs comparing people with type I diabetes vs. controls. The p-values from these separate analyses are given in Table 12.44.

Table 12.44: Effects of 10 SNPs on type I diabetes

 p-value p-value SNP SNP .04 .10 .40 .55 .34 .62 .001 .01 4 .80 .005 10

p-value p-value SNP SNP .04 .10 .40 .55 .34 .62 .001 .01 4 .80 .005 10

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