What is the estimated rate of increase in bone density of the lumbar spine per year? What is the standard error of the estimated rate of increase per year? 

Endocrinology

A 65-year-old woman with low bone density in 2002 was treated with alendronate through the year 2009. Bone density was measured irregularly over this period. The results for change in bone density of the lumbar spine are shown in Table 11.24.

Table 11.24: Change in bone density, lumbar spine, over time

 

Bone density, lumbar spine (g/cm) (x) Time from baseline Visit () (months) (t) 0.797 0.806 18 0.817 48 4 0.825 5 64 0.837 66 0.841 79 0.886 92 8. 0.881 E; = 375, Ex; = 6.69, E7 = 25,849, i=8 i=1 i=1