Terfenadine is an antihistaminic drug that contains two alcohol functional groups. Suppose terfenadine were to undergo acid-catalyzed
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Terfenadine is an antihistaminic drug that contains two alcohol functional groups. Suppose terfenadine were to undergo acid-catalyzed alcohol dehydration (Sec. 10.2).
Which alcohol would dehydrate most rapidly? Why? What would be the dehydration product?
Transcribed Image Text:
OH N-CH₂CH₂CH₂CH- terfenadine Т OH -C(CH3)3
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The question is essentially WhichOH group when protonated and lost as water Sec 102A gives the more ...View the full answer
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