Some enzymes are inhibited by high concentrations of their own substrates. (a) Show that when substrate inhibition
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Some enzymes are inhibited by high concentrations of their own substrates.
(a) Show that when substrate inhibition is important the reaction rate v is given by
where KI is the equilibrium constant for dissociation of the inhibited enzyme– substrate complex.
(b) What effect does substrate inhibition have on a plot of 1/v against 1/[S]0?
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Related Book For 
Physical Chemistry Thermodynamics And Kinetics
ISBN: 9781464124518
10th Edition
Authors: Peter Atkins, Julio De Paula
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