Key step in the biosynthesis of triglycerides (fats) is the conversion of glycerol to glycerol-1-phosphate by ATP:
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Key step in the biosynthesis of triglycerides (fats) is the conversion of glycerol to glycerol-1-phosphate by ATP: Glycerol + ATP → glycerol-1-phosphate + ADP At a steady state in the living cell, [ATP] = 10-3 M and [ADP] = 10-4 M. The maximum (equilibrium) value of the ratio [glycerol-1-p]/[glycerol] is observed to be 770 at 25ºC and pH 7.
a) Calculate K' and ∆Gº' for the reaction.
b) Using the value of ∆Gº' for the reaction ADP + Pi → ATP + H2O, together with the answer to part a), calculate the ∆Gº' and K' for the reaction glycerol + phosphate glycerol-1-phosphate + H2O.
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