1. DNP student Frieda is interested in practice-generated evidence. She was able to obtain data from 46 oncology patients from her hospital's electronic health record. All the patients received chemotherapy prior to surgery. One of the purposes of chemotherapy was to shrink the size of the tumor. Frieda wants to compare the size of the tumor at diagnosis (measured in cm) with the size of the tumor following chemotherapy to quantify this outcome of care. Which of the following tests should Frieda use to make this comparison?

One sample t test, non-directional

One sample t test, directional

Paired samples t test

Independent groups t test

Any of the above will work

2 Frieda compared the size of the tumor at diagnosis with the size of the tumor following chemotherapy using a t test. She found M before

= 2.3 cm ( S before = 0.5 cm) and M after = 1.5 cm ( S after = 0.6 cm), t(45) = 3.14, p < .05. Which of the following is a correct interpretation of the results?

There no statistically significant reduction in tumor size by the end of chemotherapy.

There was a statistically significant reduction in tumor size by the end of chemotherapy.

None of the above