1. Figure 5.1 A presented abbreviated pedigrees looking at the inheritance of X-linked human conditions. The...
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1. Figure 5.1 A presented abbreviated pedigrees looking at the inheritance of X-linked human conditions. The pedigree shows a male who was color blind and had hemophilia A. The grandsons and great-grandsons of this male were either color blind and had hemophilia A, or they had neither condition. a) Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? b) Do the genes responsible for color blindness and hemophilia A segregate independently? c) If you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia A, do you think any grandsons or great-grandsons would ever have one condition but not the other? (a) (b) || IV ||| 88- AAN 88N 2 On POND 88. 6 +8800 Male Female Hemophilia A Hemophilia B Color blind Hemophilic and color blind 4 Figure 5.1 Color blindness and two forms of hemophilia are X-linked traits. (a) Transmission of red-green color blindness and hemophilia A. The traits travel together through the pedigree, indicating their genetic linkage. (b) Transmission of red-green color blindness and hemophilia B. The mutant alleles are inherited together in only one of four grandsons. These pedigrees suggest that the gene for color blindness is close to the hemophilia A gene but far away from the hemophilia B gene. Figure 5.1b initiated with a male who was color blind and had hemophilia B. The grandsons of this male were either only color blind, only had hemophilia B, had both conditions, or they had neither condition. d) Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? e) f you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia B, do you think it is possible that the genes responsible for these two conditions would be genetically linked? f) What can you conclude about the distance between colorblindness and Hemophilia A and B? Is one of the Hemphilias closer to the colorblindness gene? 1. Figure 5.1 A presented abbreviated pedigrees looking at the inheritance of X-linked human conditions. The pedigree shows a male who was color blind and had hemophilia A. The grandsons and great-grandsons of this male were either color blind and had hemophilia A, or they had neither condition. a) Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? b) Do the genes responsible for color blindness and hemophilia A segregate independently? c) If you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia A, do you think any grandsons or great-grandsons would ever have one condition but not the other? (a) (b) || IV ||| 88- AAN 88N 2 On POND 88. 6 +8800 Male Female Hemophilia A Hemophilia B Color blind Hemophilic and color blind 4 Figure 5.1 Color blindness and two forms of hemophilia are X-linked traits. (a) Transmission of red-green color blindness and hemophilia A. The traits travel together through the pedigree, indicating their genetic linkage. (b) Transmission of red-green color blindness and hemophilia B. The mutant alleles are inherited together in only one of four grandsons. These pedigrees suggest that the gene for color blindness is close to the hemophilia A gene but far away from the hemophilia B gene. Figure 5.1b initiated with a male who was color blind and had hemophilia B. The grandsons of this male were either only color blind, only had hemophilia B, had both conditions, or they had neither condition. d) Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? e) f you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia B, do you think it is possible that the genes responsible for these two conditions would be genetically linked? f) What can you conclude about the distance between colorblindness and Hemophilia A and B? Is one of the Hemphilias closer to the colorblindness gene?
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Related Book For
Principles of Genetics
ISBN: 978-1119142287
7th edition
Authors: D. Peter Snustad, Michael J. Simmons
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