1 Some of you may know from personal experience that quitting smoking is difficult. Many people...

  

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1 Some of you may know from personal experience that quitting smoking is difficult. Many people trying to quite use nicotine replacement methods like nicotine patches or nicotine gum to ease nicotine withdrawal symptoms. Recently, medical researchers have begun investigating whether the use of an antidepressant medication might be a more effective aid to those attempting to give up cigarettes. Dr. Douglas Jorenby and colleagues compared the effectiveness of nicotine patches to the effectiveness of the antidepressant buproprion, which is marketed with the brand name Zyban. A total of 893 participants were randomly allocated to three treatment groups: placebo (A placebo looks like the real drug but has no active ingredients, such as sugar pill), nicotine patch, and Zyban. The following figure shows 95% confidence intervals for proportion not smoking after six months after the start of the experiment. a. Interpret 95% confidence interval of Zyban. b. Comparing to the 95% confidence interval of Placebo, what might you conclude in terms of effectiveness of Zyban? C. Interpret 95% confidence interval of nicotine patch. d. Comparing to the 95% confidence interval of Placebo, what might you conclude in terms of effectiveness of nicotine patch? Zyban Nicotine Patch Placebo 0.10 0.15 0.20 0.25 0.30 0.35 0.40 0.45 Proportion not smoking Figure 1. 95% confidence intervals for proportions not smoking after six months 1 Some of you may know from personal experience that quitting smoking is difficult. Many people trying to quite use nicotine replacement methods like nicotine patches or nicotine gum to ease nicotine withdrawal symptoms. Recently, medical researchers have begun investigating whether the use of an antidepressant medication might be a more effective aid to those attempting to give up cigarettes. Dr. Douglas Jorenby and colleagues compared the effectiveness of nicotine patches to the effectiveness of the antidepressant buproprion, which is marketed with the brand name Zyban. A total of 893 participants were randomly allocated to three treatment groups: placebo (A placebo looks like the real drug but has no active ingredients, such as sugar pill), nicotine patch, and Zyban. The following figure shows 95% confidence intervals for proportion not smoking after six months after the start of the experiment. a. Interpret 95% confidence interval of Zyban. b. Comparing to the 95% confidence interval of Placebo, what might you conclude in terms of effectiveness of Zyban? C. Interpret 95% confidence interval of nicotine patch. d. Comparing to the 95% confidence interval of Placebo, what might you conclude in terms of effectiveness of nicotine patch? Zyban Nicotine Patch Placebo 0.10 0.15 0.20 0.25 0.30 0.35 0.40 0.45 Proportion not smoking Figure 1. 95% confidence intervals for proportions not smoking after six months