16. Medicinal chemists make slight modifications to molecules in the attempt to increase the efficacy of...

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16. Medicinal chemists make slight modifications to molecules in the attempt to increase the efficacy of the potential drug while also decreasing toxicity and side effects. Lansoprazole (Prevacid) is a proton-pump inhibitor that is used in the treatment of ulcers. Would the proton indicated in lansoprazole be more or less acidic than the proton indicated in the analogous compound? Would these compounds be more likely to act as an acid or a base? lansoprazole analogue 16. Medicinal chemists make slight modifications to molecules in the attempt to increase the efficacy of the potential drug while also decreasing toxicity and side effects. Lansoprazole (Prevacid) is a proton-pump inhibitor that is used in the treatment of ulcers. Would the proton indicated in lansoprazole be more or less acidic than the proton indicated in the analogous compound? Would these compounds be more likely to act as an acid or a base? lansoprazole analogue