2. The spaces between endothelial cells allow nutrients and fluid to pass through these openings. We are interested in determining the flux of glucose through these junctions in the venous end of a capillary bed. Consider an endothelial cell of thickness 1.5 um. Let a paracellular pore pass between two adjacent cells. Let the radius of this pore be 5 nm. The fluid within this channel has the properties of saline. Let the pressure in the blood be 20 mm Hg (gauge pressure) while the pressure in the tissue is approximately atmospheric pressure. The concentration of glucose in the blood is 5.5 mM (1 mg/ml), while the concentration of glucose in the tissue is zero (it is taken up by the cells there). The diffusion coefficient of glucose in the pore is 5x10 cm-/sec. Estimate the flux of glucose passing through one of these pores from the blood to the tissue. Blood 10 nm Tissue 1.5 um 2. The spaces between endothelial cells allow nutrients and fluid to pass through these openings. We are interested in determining the flux of glucose through these junctions in the venous end of a capillary bed. Consider an endothelial cell of thickness 1.5 um. Let a paracellular pore pass between two adjacent cells. Let the radius of this pore be 5 nm. The fluid within this channel has the properties of saline. Let the pressure in the blood be 20 mm Hg (gauge pressure) while the pressure in the tissue is approximately atmospheric pressure. The concentration of glucose in the blood is 5.5 mM (1 mg/ml), while the concentration of glucose in the tissue is zero (it is taken up by the cells there). The diffusion coefficient of glucose in the pore is 5x10 cm-/sec. Estimate the flux of glucose passing through one of these pores from the blood to the tissue. Blood 10 nm Tissue 1.5 um