3. One method for synthesizing polypeptide chains is through the use of the Merrifield resin synthesis....
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3. One method for synthesizing polypeptide chains is through the use of the Merrifield resin synthesis. () Write the complete synthetic route for the synthesis of the tripeptide L-phenylalanine-L-selenocysteine-l-asparagine (FUN) using this method. You do not need to show any mechanisms, but you must (in show all synthetic intermediates. To reduce the time needed to answer this question, you may write the full structure of each amino acid only once and then abbreviate thereafter. You may also make any other logical abbreviations you feel appropriate - for example: abbreviating the structure of the resin once it has been shown once. However, you must write the full structure of the tripeptide formed at the end of the synthesis. (32 points): 3. One method for synthesizing polypeptide chains is through the use of the Merrifield resin synthesis. () Write the complete synthetic route for the synthesis of the tripeptide L-phenylalanine-L-selenocysteine-l-asparagine (FUN) using this method. You do not need to show any mechanisms, but you must (in show all synthetic intermediates. To reduce the time needed to answer this question, you may write the full structure of each amino acid only once and then abbreviate thereafter. You may also make any other logical abbreviations you feel appropriate - for example: abbreviating the structure of the resin once it has been shown once. However, you must write the full structure of the tripeptide formed at the end of the synthesis. (32 points):
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Answer i The synthesis of a peptide of significant length eg ten residues by this approach requires ... View the full answer
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