Question: The reversible binding interaction between a protein (P) and a ligand (L) to fom a protein-ligand complex (P-L), is described by the following equation

The reversible binding interaction between a protein (P) and a ligand (L) 

The reversible binding interaction between a protein (P) and a ligand (L) to fom a protein-ligand complex (P-L), is described by the following equation k P+ L PL k, Which of the following pairs of association and dissociation rate constants would result in the highest affinity binding? Select one alternative: O k, = 10 s and k, = 10 s Ok, = 10 s 1 and k, = 100s 94-100 s and K,- 10 s Ok, = 10 sand k, = 5 s

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