Question: (8 pts) Differential pulse voltammetry at a carbon working electrode is used to determine the concentrations of ascorbic acid and caffeine in drug formulations. In
(8 pts) Differential pulse voltammetry at a carbon working electrode is used to determine the concentrations of ascorbic acid and caffeine in drug formulations. In a typical analysis a 0.9183-g tablet is crushed and ground into a fine powder. A 0.5630-g sample of this powder is transferred to a 100-ml volumetric flask, brought into solution, and diluted to volume. A 0.500-ml portion of this solution is then transferred to a voltammetric cell that contains 20.00 mL of a suitable supporting electrolyte. The resulting voltammogram gives peak currents of 1.40 MA and 3.88 MA for ascorbic acid and for caffeine, respectively. A 0.500-ml aliquot of a standard solution that contains 250.0 ppm ascorbic acid and 200.0 ppm caffeine is then added. A voltammogram of this solution gives peak currents of 2.80 mA and 8.02 HA for ascorbic acid and caffeine, respectively. Report the milligrams of ascorbic acid and milligrams of caffeine in the tablet. (Note 1:1 ppm -0.001 mg/ml. Note 2. mind the mass of the tablet and the mass of the sample are different!)
Step by Step Solution
There are 3 Steps involved in it
Get step-by-step solutions from verified subject matter experts
