Question: A basic drug with a pka value of 7.5 is dissolved in buffer of pH 5.2. If the true octanol/water partition coefficient is 135, calculate
A basic drug with a pka value of 7.5 is dissolved in buffer of pH 5.2. If the true octanol/water partition coefficient is 135, calculate the apparent partition coefficient for the octanol/buffer. 0.67 7.78 O 8.87 0.07 6.70
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