Question: a) Select a suitable operating velocity for the column and calculate the pressure drop you would expect to observe at this velocity. b) You are

a) Select a suitable operating velocity for the column and calculate

a) Select a suitable operating velocity for the column and calculate the pressure drop you would expect to observe at this velocity.

b) You are asked to scale up the column design, increasing its capacity by quadrupling the column diameter. How might this affect critical velocity and why? Consequently, how might the design or operating parameters need to be modified?

The relationship between flow rate and pressure drop has been investigated in a chromatography column with the following parameters: The data generated is shown below

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