a) Suggest suitable reagent(s) to perform the desired cross-coupling reaction. (1 mark) 

b) Although the vinyl stannane (E) is easily generated, it is not the only reagent capable of participating in the reaction. Demonstrate your knowledge of cross-coupling reactions by suggesting a plausible variant of (E) that will engage in the reaction, but does not contain tin. (1 mark) 

c) Demonstrate your knowledge of cross-coupling reactions by drawing a plausible mechanism for the Stille cross-coupling reaction of (D) and (E). (8 marks)

Transcribed Image Text:

Br ÕBn Ó. MeO. (D) reagents OBn O, OBn (F) OBn MeO, SnBu3 (E) Br ÕBn Ó. MeO. (D) reagents OBn O, OBn (F) OBn MeO, SnBu3 (E)

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