ACTIVITY 4 INSTRUCTIONS Use the answer sheet at the end of the document to submit your answers the questions below. 1. Suppose that in a given region in 2020, there were 500 fetal deaths at 28 or more weeks of gestation, and 200 newborns who died within the first 7 days of life. The number of live births was 150,000. What is the perinatal mortality rate? 2. A case-control study of 2000 participants looked at the association between an approved drug and gallbladder cancer. The study included 700 cases. There were 200 cases and 70 controls taking Tamoxifen. Construct the 2 by 2 table and Calculate the odds ratio for contracting gallbladder cancer in the study 3. Suppose you have been asked to study the effects of stress across the lifespan of people who have a close family member with HIV/AIDS. The study is to be from the time of diagnosis until the death of the family member. Additionally, identify family members of persons without HIV/AIDS. The family members between the two groups should be similar in age, sex, race/ethnicity, and other factors, with the exception of being associated with someone with HIV/AIDS. Design an appropriate study and compare stress levels between the two groups over time. Explain and justify the study design chosen. Answer must be at least 3 complete sentences. 4. Discuss the advantages and disadvantages of hospital, general population, and special population controls in a case-control study. Answer must be at least 3 complete sentences 5. Compare and contrast effect modification with confounding