Question: Explain why low temperatures is used in the reaction? - include the possible products that can form if high temperature was used. How is reprotonation
Explain why low temperatures is used in the reaction?
- include the possible products that can form if high temperature was used.
How is reprotonation of the carbonate anion prevented? What reaction conditions were used to prevent this?
1) 4-methylvaleric acid, THF, Et3N, Pivaloyl chloride, 0C 2) n-BuLi, THF, 78c
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