Question: (20 points) San Luis Valley syndrome, also known as Recombinant 8 is caused by a chromosome inversion that includes the centromere (pericentric) of chromosome

(20 points) "San Luis Valley syndrome", also known as "Recombinant 8" is

(20 points) "San Luis Valley syndrome", also known as "Recombinant 8" is caused by a chromosome inversion that includes the centromere (pericentric) of chromosome 8 in humans (let us say region BCD on the chromosome below). Individuals with this syndrome tend to be concentrated in the Southwest US. A) Diagram the meiotic pairing that would lead to a child with this syndrome (clearly label your drawing) and B) explain why some children in a family with normal parents might be born with this severe genetic abnormality while others in the family would not. C) Why does this syndrome seem to be restricted to the southwest US? A B C DE F

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