Glomerular Filtration in the Bowman's capsule of the kidney can be described as a fluid flux...

 

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Glomerular Filtration in the Bowman's capsule of the kidney can be described as a fluid flux out of the arterial vasculature into the kidney tubular network. Under given conditions, the hydrostatic pressure in the glomerular capillaries is 55 mmHg, the hydrostatic pressure in the kidney tubular network is 15 mmHg and the osmotic pressure difference (AM) between the two compartments results in a net osmotic pressure of 30 mmHg that resists glomerular filtration (where "glomerular filtration" = fluid flow from glomerular capillaries into tubule network). Show all work for credit. Efferent arteriole Glomerular capillaries Afferent arteriole Tubular network Bowman's cap PH 55 AII-30 All pressures in mmHg Pr 15 Net driving pressure causes filtration. • If the osmotic pressure (M) in the glomerular capillaries is 5822 mmHg then what is the osmotic pressure in the kidney tubular network? Assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one ( = 1 & 0=1) • Calculate the osmolarity (osmol/L) of the filtrate in the kidney tubular network if you assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one (0 = 1 & σ=1)? • If the hydraulic permeability/conductivity (Lp) of the glomerular capillary wall is 0.003 cm mmHg- 1 s-1 then what is the flux of filtrate entering the kidney tubule network? (give your answer in cm/s). Assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one (0 = 1 & 0=1) Glomerular Filtration in the Bowman's capsule of the kidney can be described as a fluid flux out of the arterial vasculature into the kidney tubular network. Under given conditions, the hydrostatic pressure in the glomerular capillaries is 55 mmHg, the hydrostatic pressure in the kidney tubular network is 15 mmHg and the osmotic pressure difference (AM) between the two compartments results in a net osmotic pressure of 30 mmHg that resists glomerular filtration (where "glomerular filtration" = fluid flow from glomerular capillaries into tubule network). Show all work for credit. Efferent arteriole Glomerular capillaries Afferent arteriole Tubular network Bowman's cap PH 55 AII-30 All pressures in mmHg Pr 15 Net driving pressure causes filtration. • If the osmotic pressure (M) in the glomerular capillaries is 5822 mmHg then what is the osmotic pressure in the kidney tubular network? Assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one ( = 1 & 0=1) • Calculate the osmolarity (osmol/L) of the filtrate in the kidney tubular network if you assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one (0 = 1 & σ=1)? • If the hydraulic permeability/conductivity (Lp) of the glomerular capillary wall is 0.003 cm mmHg- 1 s-1 then what is the flux of filtrate entering the kidney tubule network? (give your answer in cm/s). Assume that the osmotic coefficient and the reflection coefficient for all osmotically active solutes are equal to one (0 = 1 & 0=1)