help me please

4 Multiple Choice 1 point Prion proteins O A single mutation in a gene in a somatic cell for a prion protein can cause that protein to induce misfolding in other prion proteins Prion proteins are the leading cause of Alzheimer's disease A single mutation in a gene in a somatic cell for a prion protein can cause a hereditary mutation in families OO The prion protein is an infectious agent that in its native folding form can lead to amyloid plaques. 5 True or False 1 point Ap peptide is usually degraded by the cell, but in people with Alzheimer's disease it aggregates and forms plaques True False 6 Multiple Answer 1 point Which are true of hemoglobin (multiple answers possible) O The functional form of hemoglobin is a heterotetramer Hemoglobin is composed largely of alpha helical secondary structures folded into a globular tertiary structure O In order to be functional hemoglobin must also bind an organic molecule called heme. 0 The sickle cell mutation is due to a truncation of one of the hemoglobin monomers 7 Multiple Answer 1 point Protein structural domains... Are combinations of secondary structure motifs like the helix-turn-helix domain often fold separately from the rest of the protein are stable sub-structures in a portion that appear in many different proteins B Multiple Answer 1 point Which are true of protein folding? (multiple possible) O A "denatured" protein can be "renatured" given appropriate conditions O The free energy of the correctly folded protein is at its minimum O All of the information necessary to fold a protein correctly is in its amino acid sequence 9 Multiple Choice 1 point Chaperones are proteins that O help get proteins out of nonfunctional minimal energy states to their proper native state interact with DNA to form nucleosomes O Are what allow amino acids to interact locally in protein folding. O help most proteins fold correctly