How does a substitution differ from a mutation?

Group of answer choices

A substitution is a change in a nucleotide that has spread through the population based on evolutionary forces, whereas a mutation is a change in a nucleotide in a single invididual.

A substitution is a change in a nucleotide in a single individual, whereas a mutation is a change in a nucleotide that has spread through the population based on evolutionary forces.

Substitutions occur more frequently than mutations.

Substitutions can only occur via non$-$random processes $($e$.$g$.,$ natural selection$),$ whereas mutation is random.