Question: In an MTD tox study, a dog was given 40 mg/kg of drug substance after the 20 mg/kg dose. The 40 mg/kg resulted in


In an MTD tox study, a dog was given 40 mg/kg of drug substance after the 20 mg/kg dose. The 40 mg/kg resulted in emesis. What is the MTD? Three doses used in a 28 day tox study (using the above MTD tox Study) were: MTD dose, MTD dose/2 MTD dose/4 Equation: Aggregate dose = MTD dose + MTD dose/2 + MTD dose/4 What is the Aggregate Dose? Aggregate Dose = How much drug substance is required for a 28-day tox study with an overage of 1.1 using 20 dogs based on the Aggregate dose? QUESTION 2 a) Define Primitive data type. b) List TWO (2) types of Recursive cases. c) State TWO (2) disadvantages of an array list. d) Give ONE (1) difference between Perfect binary tree and Full binary tree. e) State the output from a method public void pop () in Stack. f) List ONE (1) example of non-linear data structure. g) Define Tail recursive. (2 marks) (2 marks) (2 marks) (2 marks) (2 marks) (2 marks) (2 marks)
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