Intent- to- treat analysis shows no significant difference in outcome between intervention and control groups in a
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Question:
Intent- to- treat analysis shows no significant difference in outcome between intervention and control groups in a randomized clinical trial, using a simple 2x2 table. You have recorded the occurrence and time of events (outcome) and loss to follow up. You notice that 40% in each group were lost to follow up over the 3 years of trial duration.
1) Discuss the potential impact of loss to follow-up on the results of your trial.
2) What other analysis can you perform?
Related Book For
Probability and Statistics
ISBN: 978-0321500465
4th edition
Authors: Morris H. DeGroot, Mark J. Schervish
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