Question: Intent- to- treat analysis shows no significant difference in outcome between intervention and control groups in a randomized clinical trial, using a simple 2x2 table.

Intent- to- treat analysis shows no significant difference in outcome between intervention and control groups in a randomized clinical trial, using a simple 2x2 table. You have recorded the occurrence and time of events (outcome) and loss to follow up. You notice that 40% in each group were lost to follow up over the 3 years of trial duration.

1) Discuss the potential impact of loss to follow-up on the results of your trial.

2) What other analysis can you perform?

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